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Laura McAdam, MSc, MD, FRCPC

Laura McAdam, MSc, MD, FRCP(C)

Clinician Investigator, Physician Director, Ambulatory Care

Dr. Laura McAdam is a pediatrician at Holland Bloorview Kids Rehabilitation Hospital. Her clinical focus is rare genetic conditions specifically with children who have neuromuscular conditions or Rett syndrome. Dr. McAdam is also the Physician Director of Ambulatory Care at Holland Bloorview. She has successfully completed the Advanced Health Leadership Program through the Rotman School of Management Executive program at the University of Toronto and has completed the Global Clinical Scholars Research Training Program through the Office of Global Education at Harvard Medical School.

Research

Dr. McAdam's research focuses on three main areas: enhancing clinical care for children with neuromuscular conditions, advancing rehabilitation for children with rare diseases, and understanding the broader psychosocial impact of living with a rare condition. To achieve these goals, she leads investigator driven research projects focusing on rehabilitation, collaborates nationally and internationally in studies investigating natural history and chronic corticosteroid treatment effects, and participates in clinical trials. Through her research she seeks to bridge knowledge gaps, improve patient care, and address the multi-faceted challenges faced by individuals with rare diseases and their caregivers. 


Education & Profession

Education:

  • M.D., University of Toronto, Toronto, Ontario FRCP C, Royal College of Physicians & Surgeons of Canada, Ottawa, Ontario. Pediatrics. 
  • M. Sc., University of Toronto, Toronto, Ontario. Physiology, Program of Neuroscience
  • B. Sc., Queen's University, Kingston, Ontario

Professional Memberships:

  • Canadian Medical Association Ontario
  • College of Physicians and Surgeons Ontario
  • Medical Association Royal College of Physicians & Surgeons of Canada
  • World Muscle Society

University Positions / Affiliations:

  • Assistant Professor, University of Toronto, Toronto, Ontario , Department of Pediatrics, Division of Development

Current Projects

Co-creating a practical therapy resource for rehabilitation therapists working with children with Spinal Muscular Atrophy (SMA) treated with genetic based therapies (recruitment coming soon)

Rehabilitation strategies for children with SMA treated with genetic based therapies (recruiting)

Canadian Neuromuscular Disease Registry (CNDR)(recruiting)

Rett Syndrome Clinical Registry (recruitment coming soon)

Givinostat and Boys with Duchenne Muscular Dystrophy

  • Open label, long-term safety, tolerability, and efficacy study of GIVINOSTAT in all DMD patients who have been previously treated in one of the GIVINOSTAT studies (recruitment closed)

  • Randomised, double-blind, placebo-controlled, multicentre study to evaluate the efficacy, safety and tolerability of givinostat in non-ambulant patients with Duchenne Muscular Dystrophy (recruitment coming soon) 


Publications

Click to see Laura McAdams's publications on PubMed

Click to see Laura McAdam's publications on Google Scholar


Contact Info

Holland Bloorview Kids Rehabilitation Hospital 
150 Kilgour Road, Toronto ON, M4G 1R8 
Tel: 416-425-6220 x.6123

Research Inquiries: 

Contact the research team at neuromuscular.research@hollandbloorview.ca

Clinic inquiries: 

Neuromuscular Services 

Rett Syndrome Clinic