Evdokia Anagnostou

Evdokia Anagnostou

Senior Clinician Scientist, Professor, Department of Paediatrics, University of Toronto, Canada Research Chair (Tier II) in Translational Therapeutics in Autism

Visit the Autism Research Centre


Research

Centre for Leadership:

Child Development

Research Focus:

Dr. Anagnostou’s research focuses on improving outcomes and quality of life for children with autism spectrum disorders and their families.

Research Focus (Academic Version)

Dr. Anagnostou studies how genes affect brain structure/function, behaviour, cognition and health in children and adults with neurodevelopmental disorders.  Then she works to translate this information to new intervention.


Education & Profession

Education:

  • M.D. Medicine, McGill University (1998) 

  • B.Sc Chemistry, Stevens Institute of technology (1994) 

  • Graduate Certificate, Chemical Physiology, Stevens Institute of Technology (1994)

Professional Memberships:

  • Canadian Association of Neuroscience
  • American Academy of Neurology
  • International Child Neurology Association
  • Society of Neuroscience
  • Child Neurology Society
  • International Society of Autism Research

University Positions / Affiliations:

  • Professor, Department of Paediatrics, University of Toronto 

  • Full time Member, Institute of Medical Sciences, University of Toronto

  • Adjunct Scientist, Research Institute, The Hospital for Sick Children

  • Adjunct Assistant Professor, Psychiatry, Mount Sinai School of Medicine

Honours and Awards:

INTERNATIONAL

2018 - 2019     Elected Chair: International Autism Society for Autism Research (INSAR) meeting

2006  ECNP Poster Award, Principal Author, European College of Neuropsychopharmacology, Paris, France.  fMRI emotional response inhibition in ASD. Total Amount: 500 EUR

2006 - 2008   Seaver Young Investigator Award, Principal Investigator, Seaver and New York Autism Centre of Excellence, New York, United States. Oxytocin in ASD. Total Amount: 31,875 USD

2006 - 2008   Young Investigator Award, Principal Investigator, NARSAD, New York, United States. Imaging of ASD. Total Amount: 60,000 USD

NATIONAL

2018 The Gerry Bloomfield Award for outstanding contributions to the MCYS Ontario Autism Program Advisory  Committee. Autism Ontario.

2017 The Gerry Bloomfield Professional Award, Autism Ontario. For Outstanding Professional Contributions to the field of Autism Spectrum Disorders (ASD).

2016 Dr. Stuart D. Sims Chair in Autism, Holland Bloorview Kids Rehabilitation Hospital & University of Toronto. Total Amount: 3,000,000 CAD 

2014 Canada Research Chair - Tier 2, Translational Therapeutics in ASD, Canada Research Chair, Canadian  Institutes of Health Research (CIHR). Total Amount: 500,000 CAD

1998 Chambre de Commerce Hellenique Award, Student, Chambre de Commerce, Montreal, Quebec. For academic excellence and personal distinction. Total Amount: 1,000 CAD

Teaching and Education Awards

LOCAL

2017 Paul Steinhauer Award, Teacher, Division of Child & Youth Mental Health, Dept of Psychiatry,  University of  Toronto. (Postgraduate MD)
 
2009 Teaching Award, Teacher, Developmental Paediatrics, Dept of Pediatrics, Faculty of Medicine, University of Toronto. (Postgraduate MD, Subspecialty) 


Current Projects

Behavioural Intervention

Characterizing Autism

Genetics

Medication Clinical Trials


Publications

Click to see Dr. Evdokia Anagnostou's publications on PubMed.

PEER-REVIEWED PUBLICATIONS

Journal Articles (underline suggest student in Anagnostou's lab)

2019

  • Mogadam A, Keller AE, Arnold PD, Schachar R, Lerch JP, Anagnostou E, Pang EW.  Magnetoencephalographic (MEG) brain activity during a mental flexibility task suggests some shared neurobiology in children with neurodevelopmental disorders. Journal of Neurodevelopmental Disorders. 2019 Aug 19;11(1):19. Coauthor or Collaborator.
  • Carbonell AU, Cho CH, Tindi JO, Counts PA, Bates JC, Erdjument-Bromage H, Cvejic S, Iaboni A, Kvint I, Rosensaft J, Banne E, Anagnostou E, Neubert TA, Scherer SW, Molholm S, Jordan BA.  Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.  Nature Communications, 6 Aug 2019; 10(1):3529. Coauthor or Collaborator.
  • Le Duc D, Giulivi C, Hiatt SM, Napoli E, Panoutsopoulos A, Harlan De Crescenzo A, Kotzaeridou U, Syrbe S, Anagnostou E, Azage M, Bend R, Begtrup A, Brown NJ, Büttner B, Cho MT, Cooper GM, Doering JH, Dubourg C, Everman DB, Hildebrand MS, Santos FJR, Kellam B, Keller-Ramey J, Lemke JR, Liu S, Niyazov D, Payne K, Person R, Quélin C, Schnur RE, Smith BT, Strober J, Walker S, Wallis M, Walsh L, Yang S, Yuen RKC, Ziegler A, Sticht H, Pride MC, Orosco L, Martínez-Cerdeño V, Silverman JL, Crawley JN, Scherer SW, Zarbalis KS, Jamra R.  Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size. Brain, A Journal of Neurology, 1 Sep 2019; 142(9):2617-2630. Coauthor or Collaborator.
  • Chater-Diehl E, Ejaz R, Cytrynbaum C, Siu MT, Turinsky A, Choufani S, Goodman SJ, Abdul-Rahman O, Bedford M, Dorrani N, Engleman K, Flores-Daboub J, Genevieve D, Mendoza-Londono R, Meschino W, Perrin L, Safina N, Townshend S, Scherer SW, Anagnostou E, Piton A, Deardorff M, Brudno M, Chitayat D, Weksberg R.  New insights into DNA methylation signatures: SMARCA2 variants in Nicolaides-Baraitser syndrome.  BMC Med Genomics, 9 Jul 2019; 12(1):105. Coauthor or Collaborator.
  • Mahendiran T, Dupuis A, Crosbie J, Georgiades S, Kelley E, Liu X, Nicolson R, Schachar R, Anagnostou E. and Brian J. Sex Differences in Social-Adaptive Function in Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder. Frontiers in Psychiatry: Child & Adolescent Psychiatry, 12 Sept 2019 (Trainee publication, Mahendiran T.) Co-author or Collaborator.
  • Jachyra, P., Anagnostou, E., Petta, C., Cosgrove, S., Chen, L., Capano, L., Molitisanti, L., Knibbe, TJ, & McPherson AC. Girl’s don’t have big tummies: Children’s experiences of discussing weight-related topics in healthcare consultations. Autism, July 2019, 23(5): 1095-1105. (Trainee publication, Jachyra, P.) Coauthor or Collaborator.
  • Garfunkel D, Anagnostou E, Aman MG, Handen BL, Sanders KB, Macklin EA, Chan J, Veenstra-VanderWeele J. Pharmacogenetics of Metformin for Medication-Induced Weight Gain in Autism Spectrum Disorder.  J. Child Adolescent Psychopharmacology, 2019 Aug; 29(6): 448-455. Coauthor or Collaborator.
  • Penner M, Anagnostou E, Andoni LY & Ungar WJ. Environmental Scan of Canadian and United Kingdom (UK) policies for autism spectrum disorder diagnostic assessment. Paediatrics and Child Health. 2019 Jun; 24(3): e125-e134. Coauthor or Collaborator.
  • Bedford S, Park MTM, Devenyi GA, Tullo S, Germann J, Patel R, Anagnostou E, Baron-Cohen S, Bullmore ET, Chura LR, Craig MC, Ecker C, Floris DL, Holt RJ, Lenroot R, Lerch JP, Lombardo MV, Murphy DGM, Raznahan A, Ruigrok ANV, Smith E, Spencer MD, Suckling J, Taylor MJ, Thurm A; MRC AIMS Consortium, Lai MC, Chakravarty MM.  Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder. Mol Psychiatry. 2019 Apr 26. Epub ahead of print. Co-author or Collaborator.
  • Buxbaum JD, Baron-Cohen S, Anagnostou E, Ashwin C, Betancur C, Chakrabarti B, Crawley JN, Hoekstra RA, Hof PR, Lai MC, Lombardo MV, Schumann CM. Rigor in science and science reporting: updated guidelines for submission to Molecular Autism. Molecular Autism 2019 (Feb.4). 10(6): 1-5. Coauthor or Collaborator.
  • Baribeau, D.A.,Dupuis, A., Paton, T., Hammill, C., Scherer, S., Schachar, R., Arnold, P., Szatmari, P., Nicolson, R., Georgiades, S., Crosbie, J., Brian, J., Iaboni, A., Kushki, A., Lerch, J.P., Anagnostou, E. Structural Neuroimaging Correlates of Social Deficits are Similar in Autism Spectrum Disorder and Attention- Deficit/Hyperactivity Disorder: Analysis from the POND Network. Translational Psychiatry, 2019 Feb 4; 9(1):72. (Trainee publication, Baribeau, DA.). Senior Responsible Author.

2018

  • Capano L, Dupuis A, Brian J, Mankad D, Genore L, Hastie Adams R,  Smile S, Lui T, Odrobina D, Foster J, Anagnostou E. A pilot dose finding study of pioglitazone in children with autism spectrum disorder (ASD). Molecular Autism, 2018 Nov 26; 9:59 (Trainee publication, Capano L.) Senior Responsible Author.
  • Yuk,V., Urbain, C., Pang, E.W., Anagnostou, E., Buchsbaum, D., & Taylor, M.J. Do you know what I'm thinking? Temporal and spatial brain activity during a theory-of-mind task in children with autism. Developmental Cognitive Neuroscience, 2018 Nov; 34:139-147. (Trainee publication, Yuk V.) Coauthor or Collaborator.
  • Jachyra PAnagnostou E, Knibbe T.J, Petta C, Cosgrove S, Chen L, Capano L, Moltisanti L, McPherson A.C. (2018). Weighty Conversations: Caregivers', Children's, and Clinicians' Perspectives and Experiences of Discussing Weight-Related Topics in Healthcare Consultations. Autism Research/INSAR (Nov). 11(11): 1500-1510. (Trainee publication, Jachyra P.) Coauthor or Collaborator.
  • Jachyra, P., Anagnostou, E., Petta, C., Cosgrove, S., Chen, L., Capano, L., Molitisanti, L., Knibbe, TJ, & McPherson AC. Girl’s don’t have big tummies: Children’s experiences of discussing weight-related topics in healthcare consultations. Autism, Sept 2018, ePub ahead of print: 1-10. (Trainee publication, Jachyra, P.) Coauthor or Collaborator.
  • Freitas C, Manzato E, Burini A, Taylor MJ, Lerch JP, Anagnostou E. (2018). Neural Correlates of Familiarity in Music Listening: A Systematic Review and a Neuroimaging Meta-Analysis. Frontiers in Neuroscience (Oct.5). 12(686): eCollection 2018. (Trainee publication, Freitas, C.) Senior Responsible Author.
  • Germain E, Foster NEV, Sharda M, Chowdhury R, Tryfon A, Doyle-Thomas KARAnagnostou E, Hyde KL. Pitch direction ability predicts melodic perception in autism. Child Neuropsychology: Journal on Normal and Abnormal Development in Childhood and Adolescence. 2018 June 28:1-21. Coauthor or Collaborator.
  • Aman M. G., Hollway J. A., Veenstra-VanderWeele J., Handen B.L., Sanders K.B., Chan J., Macklin E., Arnold L.E., Wong T, Newsom C, Hastie Adams R., Marler S, Peleg N., and Anagnostou E. Effects of Metformin on Spatial and Verbal Memory in Children with ASD and Overweight Associated with Atypical Antipsychotic Use. Journal of Child and Adolescent Psychopharmacology. 2018 May 28(4): 266-273. Senior Responsible Author.
  • Mogadam A, Keller AE, Taylor MJ, Lerch JP, Anagnostou E, Pang EW. Mental flexibility: An MEG investigation in typically developing children. Brain and Cognition. 2018 Feb;120:58-66. Coauthor or Collaborator.
  • Lange S., Rehm J., Anagnostou E., Popova S. Prevalence of Externalizing Disorders and Autism Spectrum Disorder among Children with Fetal Alcohol Spectrum Disorder: Systematic Review and Meta- analysis. Biochemistry and Cell Biology, 2018 Apr. 96(2): 241-251. Coauthor or Collaborator.
  • Penner M., Anagnostou E, Ungar WJ. Practice patterns and determinants of wait time for autism spectrum disorder diagnosis in Canada. Molecular Autism. 2018 Mar 6:9(16): 1-13. Coauthor or Collaborator.
  • Anagnostou E. Clinical Trials in Autism Spectrum Disorder: Evidence, Challenges and Future Directions. Current Opinion in Neurology 2018 Apr; 31(2):119-125. Principal Author.
  • Leung RC, Pang EW, Anagnostou E, Taylor MJ. Young Adults with Autism Spectrum Disorder Show Early Aytpical Neural Activity during Emotional Face Processing. Frontiers in Human Neuroscience. 2018 Feb 22;12(57):1-10. Coauthor or Collaborator.
  • Xu X, Zhou TJ, Anagnostou E., Soorya L, Koleyzon A., Hof PR., Fan J. Heightened Brain Response to Pain Anticipation in Hi-Functioning Adults with Autism Spectrum Disorder. European Journal of Neuroscience. 2018 Mar; 47(6): 592-601. Coauthor or Collaborator.

2017

  • Sharda M, Foster NE, Tryfon A, Doyle-Thomas KA, Ouimet T, Anagnostou E, Evans AC, Zwaigenbaum L, Lerch JP, Lewis JD, Hyde KL. Language Ability Predicts Cortical Structure and covariance in Boys with Autism Spectrum Disorder. Cerebral Cortex, 2017 Mar.1; 27(3):1849-1862. Coauthor or Collaborator.
  • Vakorin V, Doesburg S, Leung R, Vogan V, Anagnostou E, Taylor M.  Developmental changes in neuromagnetic rhythms and network synchrony in autism. Annals of Neurology 2017 Feb; 81(2):199-211. Coauthor or Collaborator
  • Penner MAnagnostou E, Andoni LY, Ungar WJ. Systematic review of clinical guidance documents for autism spectrum disorder diagnostic assessment in select regions. Autism 2017 May 1:1362361316685879. Epub ahead of print. Coauthor or Collaborator.
  • Cameron J.M., Levandovskiy V., Roberts W, Anagnostou E, Scherer S, Loh A, Schulze A. Variability of Creatine Metabolism Genes in Children with Autism Spectrum Disorder. International Journal of Molecular Sciences, 2017Jul 31. 8(8): pii: E1665. Coauthor or Collaborator.
  • Weiner DJ, Wigdor EM, Ripke S, Walters RK, Kosmicki JA, Grove J, Samocha KE, Goldstein J, Okbay A, Bybjerg-Grauholm J, Werge T, Hougaard DM, Taylor J, iPSYCH-Broad Autism Group; Psychiatric Genomics Consortium Autism Group, Skuse D, Devlin B, Anney R, Sanders SJ, Bishop S, Mortensen PB, Børglum AD, Smith GD, Daly MJ, Robinson EB. Plus, 164 Collaborators: Bækvad-Hansen M, Dumont A, Hansen C,... Anagnostou E.(150/164) ... Arking DE. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. Nature Genetics, 2017 Jul; 49(7): 978-985. Coauthor or Collaborator.

  • Autism Spectrum Disorders Working Group of The Psychiatric Genomics Consortium. Collaborators (162): Anney RJL, Ripke S, Antitila V... Anagnostou E. (146/162) ... Daly MJ. Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. Molecular Autism; 2017 May 22. 8(21):eCollection 2017. Coauthor or Collaborator.

  • Kanner AM, Scharfman H, Jette N, Anagnostou E, Bernard C, Camfield C, Camfield P, Legg K, Dinstein I, Giacobe P, Friedman A, Pohlman-Eden B. Epilepsy as a Network Disorder (1): What can we learn from other network disorders such as autistic spectrum disorder and mood disorders?. Epilepsy & Behaviour; 2017 Dec. 77: 106-113. Coauthor or Collaborator.

  • McDougall F, Willgoss T, Hwang S, Bolognani F, Murtagh L, Anagnostou E, Rofail D. Development of a patient-centered conceptual model impact of the living with autism spectrum disorder. Autism, 2017 Sep 1:1362361317718987; ePub ahead of print: Coauthor or Collaborator.

  • Van Rooij D, Anagnostou E, Arango C, Auzjas G, Behrmann M, Busatto GF, Calderoni S, Daly E, Deruelle C, Di Martino A, Dinstein I, Duran FLS, Durston S, Ecker C, Fair D, Fedor J, Fitzgerald J, Freitag CM, Gallagher L, Gori I, Haar S, Hoekstra L, Jahanshad N, Jalbrzikowski M, Janssen J, Lerch J, Luna B, Martinho MM, McGrath J, Muratori F, Murphy CM, Murphy DGM, O'Hearn K, Oranje B, Parellada M, Retico A, Rossa P, Rubia K, Shook D, Taylor M, Thompson PM, Tosetti M, Wallace GL, Zhou F, Buitelaar JK. Cortical and Subcortical Brain Morphometry Differences Between Patients With Autism Spectrum Disorder and Healthy Individuals Across the Lifespan: Results From the ENIGMA ASD Working Group. American Journal of Psychiatry 2017 Nov.17; 175(4): 359-369. Coauthor or Collaborator.

  • Baribeau D.A., Dupuis A, Paton T.A., Scherer S.W., Schachar R.J., Arnold P.D., Szatmari P, Nicolson R, Georgiades S, Crosbie J, Brian J, Iaboni A, Lerch J, Anagnostou E. Oxytocin Receptor Polymorphisms are Differentially Associated with Social Abilities across Neurodevelopmental Disorders. Scientific Reports, 2017 Sept; 7(1):11618. Senior Responsible Author.
  • Chowdhury R, Sharda M, Foster N.E.V., Germain E, Tryfon K, Doyle-Thomas KAnagnostou E, Hyde K.L. Auditory Pitch Perception in Autism Spectrum Disorder Is Associated with Nonverbal Abilities. Perception, 2017 Jul 6; 46(11): 1298-1320. Coauthor or Collaborator.
  • C Yuen RK, Merico D, Bookman M,... Anagnostou E. (76/82) .... Scherer S. Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder. Nature Neuroscience; 2017 Apr.20; 20(4):602-611. Coauthor or Collaborator
  • Tryfon A., Foster N.E., Ouimet T., Doyle-Thomas KAnagnostou E, Sharda M, Hyde K.L. Auditory- motor rhythm synchronization in children with autism spectrum disorder. Research in Autism Spectrum Disorders, 2017 Mar. 35: 51-61. Coauthor or Collaborator
  • Handen, B.L., Anagnostou, E., Aman, M.G., Sanders, K.B., Chan, J., Hollway, J.A., Brian, J., Arnold, L.E., Capano, L., Williams, C., Hellings, J.A., Butter, E., Mankad, D., Tumuluru, R., Kettel, J., Newsom, C.R., Peleg, N., Odrobina, D., McAuliffe-Bellin, S., Marler, S., Wong, T., Wagner, A., Hadjiyannakis, S., Macklin, E.A., Veenstra-VanderWeele, J.(2017). A randomized, placebo controlled trial of metformin for the treatment of overweight induced by antipsychotic medication in young people with ASD: Open-label extension.Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), 2017 Oct. 56(10):849-856. Coauthor or Collaborator.
  • Penner M, King GA, Hartman L, Anagnostou E, Shouldice M, Hepburn CM.Community General Pediatricians' Perspectives on Providing Autism Diagnoses in Ontario, Canada: A Qualitative Study. Journal of Developmental and Behavioural Pediatrics, 2017 Oct. 38(8): 593-602.Coauthor or Collaborator.
  • Lake JK, Denton D, Lunsky Y, Shui AM, Veenstra-VanderWeele J, Anagnostou E. Medical Conditions and Demographic, Service and Clinical Factors Associated with Atypical antipsychotic Medication Use among Children with an Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 2017 May; 47(5):1391-1402.  Senior Responsible Author

2016

  • Ameis HS, Lerch JP, Taylor M, Lee W, Viviano J, Pipitone J, Nazeri A, Croarkin P, Voineskos A, Lai MC, Crosbie J, Brian J, Soreni N, Schachar R, Szatmari P, Arnold P, Anagnostou E. A Diffusion Tensor Imaging Study in Children With ADHD,Autism Spectrum Disorder, OCD, and Matched Controls: Distinct and Non-Distinct White Matter Disruption and Dimensional Brain-Behavior Relationships. American Journal of Psychiatry, 2016 Dec.1; 173(12):213-1222. Senior Responsible Author.
  • Ibrahim, G.M., Morgan, B.R, Vogan, V.M., Leung, R.C., Anagnostou, E., Taylor, M.J. Mapping the network of neuropsychological impairment in children with autism spectrum disorder: A graph theoretical analysis. Journal of Autism and Developmental Disorders (JADD); 2016 Dec; 46(12): 3770-3777. Coauthor or Collaborator.
  • Anagnostou E, Aman MG, Handen BL, Sanders KB, Shui A, Hollway JA, Brian JA, Arnold LE, Capano L, Hellings JA, Butter E, Mankad D, Tumuluru R, Kettel J, Newsom CR, Peleg N, Odrobina D, McAuliffe-Bellin S, Zakroysky P, Marler S, Wagner A, Wong T, Macklin EA, Veenstra-VanderWeele J. Metformin for the Treatment of Overweight Induced by Atypical Antipsychotic Medication in Young People With Autistic Spectrum Disorder; A Randomized Clinical Trial. JAMA psychiatry, 2016 Sept.1; 73(9):928-937. Principal author.
  • Brian JA, Doyle-Thomas K, Baribeau DAnagnostou E. Novel mechanisms and treatment approaches in autism spectrum disorder. Discovery Medicine. 2016 Aug; 22(119):47-54.Senior Responsible Author. 
  • Goldfarb C, Genore L, Hunt C, Flanagan J, Handley-Derry M, Jethwa A, Jones-Stokreef N, Kirkpatrick S.M.L., Richards A, Rojnica L, Schwartz C, Shawn D, Superina-Bell D, Young E, Anagnostou, E. Hyperbaric oxygen therapy for the treatment of children and youth with Autism Spectrum Disorders: An evidence-based systematic review. Research in Autism Spectrum Disorders; 2016 Sept-Oct;29-30:1-7. Senior Responsible Author. 
  • Cheung S, Han E, Kushki A, Anagnostou E, Biddiss E. Biomusic: An auditory interface for detecting physiological indicators of anxiety in children. Frontiers in Neuroscience, 2016 Aug30;10(401):1-10. Coauthor or Collaborator.
  • Yuen RK, Merico D, Cao H, Pellecchia G, Alipanahi B, Thiruvahindrapuram B, Tong X, Sun Y, Cao D, Zhang T, Wu X, Jin X, Zhou Z, Liu X, Nalpathamkalam T, Walker S, Howe JL, Wang Z, MacDonald JR, Chan A, D'Abate L, Deneault E, Siu MT, Tammimies K, Uddin M, Zarrei M, Wang M, Li Y, Wang J, Wang J, Yang H, Bookman M, Bingham J, Gross SS, Loy D, Pletcher M, Marshall CR, Anagnostou E, Zwaigenbaum L, Weksberg R, Fernandez BA, Roberts W, Szatmari P, Glazer D, Frey BJ, Ring RH, Xu X, Scherer SW. Genome-wide characteristics of de novo mutations in autism. NPJ Genomic Medicine. 2016 Aug;1(16027):1-10.Coauthor or Collaborator.
  • Leung RC, Vogan VM, Powell TC, Anagnostou E, Taylor MJ. The role of executive functions in social impairment in Autism Spectrum Disorder. Child Neuropsychol. 2016;22(3):336-44 (Trainee publication, Leung RC). Coauthor or Collaborator.
  • Chiu TA, Anagnostou E, Brian J, Chau T, Kushki A. Specificity of Autonomic Arousal to Anxiety in Children with Autism Spectrum Disorder. Autism Research. 2016; 9(4): 491-501 (Trainee publication, Chiu TA). Coauthor or Collaborator.
  • Vogan, V.M., Morgan, B.R., Leung, R.C., Anagnostou, E., Doyle-Thomas, K., Taylor, M.J.  Widespread white matter differences in children and adolescents with Autism Spectrum Disorder.Journal of Autism and Developmental Disorders (JADD). 2016; 46(6): 2138-2147. Coauthor or Collaborator.
  • Pang EW, Valica T, MacDonald MJ, Taylor MJ, Brian J, Lerch JP, Anagnostou E. Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder. Autism Research. 2016 Feb;9(2):249-261 (Trainee publication, Valica T). Senior Responsible Author.
  • Foster NE, Ouimet T, Tryfon A, Doyle-Thomas K, Anagnostou E, Hyde KL. Effects of Age and Attention on Auditory Global-Local Processing in Children with Autism Spectrum Disorder. J Autism Dev Disord. 2016 Jan 2. Epub ahead of print. In Press (Trainee publication, Doyle-Thomas K). Coauthor or Collaborator.
  • Schulze A, Bauman M, Tsai AC, Reynolds A, Roberts W, Anagnostou E, Cameron J, Nozzolillo AA, Chen S, Kyriakopoulou L, Scherer SW, Loh A. Prevalence of Creatine Deficiency Syndromes in Children With Nonsyndromic Autism. Pediatrics. 2016 Jan;137(1):1-9. Coauthor or Collaborator.

2015

  • Panju S, Brian J, Dupuis A, Anagnostou E, Kushki A. Atypical sympathetic arousal in children with autism spectrum disorder and its association with anxiety symptomatology. Molecular Autism. 2015 Dec 11;6:64 (Trainee publication, Panju S). Coauthor or Collaborator.
  • Traynor JM, Hanford LC, Hall GB, Rogers C, Doyle-Thomas KA, Foster N, Tryfon A, Ouimet T, Anagnostou E, Hyde K, Evans A, Zwaigenbaum L, NeuroDevNet ASD Imaging Group. Atypical thalamo-cortical resting-state connectivity is correlated with repetitive behaviours in autism spectrum disorder. Int J Dev Neurosci. 2015 Dec;47(Pt A):120 (Trainee publication, Doyle-Thomas KA). Coauthor or Collaborator.
  • Foster N, Tryfon A, Ouimet T, Doyle-Thomas KAAnagnostou E, Evans A, Zwaigenbaum L, Hyde K, NeuroDevNet ASD Imaging Group. Auditory cortical structure predicts superior pitch processing in children with autism. Int J Dev Neurosci. 2015 Dec;47(Pt A):96-97 (Trainee publication, Doyle-Thomas KA).Coauthor or Collaborator.
  • Tryfon A, Foster NE, Ouimet T, Doyle-Thomas KAnagnostou E, Evans AC, Zwaigenbaum L, Hyde KL, NeuroDevNet ASD Imaging Group. Neuroanatomical correlates of auditory-motor synchronization in children with autism. Int J Dev Neruosci. 2015 Dec;47(Pt A):74 (Trainee publication, Doyle-Thomas KA). Coauthor or Collaborator.
  • Neul JL, Glaze DG, Percy AK, Feyma T, Beisang A, Dinh T, Suter B, Anagnostou E, Snape M Horrigan J, Jones NE. Improving Treatment Trial Outcomes for Rett Syndrome: The Development of Rett-specific Anchors for the Clinical Global Impression Scale. J Child Neurol. 2015 Nov;30(13):1743-1748.Coauthor or Collaborator.
  • Foster NE, Doyle-Thomas KA, Tryfon A, Ouimet T, Anagnostou E, Evans AC, Zwaigenbaum L, Lerch JP, Lewis JD, Hyde KL and NeuroDevNet ASD imaging group. Structural Gray Matter Differences During Childhood Development in Autism Spectrum Disorder: A Multimetric Approach. Pediatr Neurol. 2015 Oct;53(4):350-359. pii: S0887-8994(15)00320-3. Epub 2015 Jun 25 (Trainee publication, Doyle-Thomas KA). Coauthor or Collaborator.
  • Baribeau DAAnagnostou E. Oxytocin and Vasopressin: Linking pituitary neuropeptides and their receptors to social neurocircuits. Frontiers in Neuroscience. 2015 Sep 24;9:335 (Trainee publication, Baribeau DA). Senior Responsible Author.
  • Tammimies K, Marshall C, Walker S, Kaur G, Thiruvahindrapuram B, Lionel A, Yuen R, Uddin M, Roberts W, Weksberg R, Woodbury-Smith M, Zwaigenbaum L, Anagnostou E, Wang Z, Wei J, Howe J, Gazzellone M, Lau L, Sung W, Whitten K, Vardy C, Crosbie V, Tsang B, D’Abate L, Tong W, Luscombe S, Doyle T, Carter M, Szatmari P, Stuckless S, Merico D, Stavropoulos D, Scherer S, Fernandez B. Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder. JAMA. 2015 Sep;314(9):895-903. Coauthor or Collaborator.
  • Gu X, Eilam-Stock T, Zhou T, Anagnostou E, Kolevzon A, Soorya L, Hof PR, Friston KJ, Fan J. Autonomic and brain responses associated with empathy deficits in autism spectrum disorder. Hum Brain Mapp. 2015 Sep;36(9):3323-3338. Epub May 2015. Coauthor or Collaborator.
  • Anagnostou E, Jones N, Huerta M, Halladay AK, Wang P, Scahill L, Horrigan JP, Kasari C, Lord C, Choi D, Sullivan K, Dawson G. Measuring social communication behaviors as a treatment endpoint in individuals with autism spectrum disorder. Autism. 2015 Jul;19(5):622-636. Epub 2014 Aug 5. Principal Author.
  • Baribeau DA, Dupuis A, Paton T, Doyle-Thomas KA, Iaboni A, Crosbie J, McGinn H, Arnold PD, Brian J, Kushki A, Nicolson R, Schachar RJ, Soreni N, Szatmari P, Anagnostou E. Examining and comparing social perception abilities across childhood onset neurodevelopmental disorders. American Academy of Child and Adolescent Psychiatry. 2015 Jun;54(6):479-486. Epub 2015 Mar 30 (Trainee publication, Baribeau DA). Senior Responsible Author.
  • Doyle-Thomas KA, Lee W, Foster NE, Tryfon A, Ouimet T, Hyde KL, Evans AC, Lewis J, Zwaigenbaum L, Anagnostou E; NeuroDevNet ASD Imaging Group. functional brain connectivity during rest in autism spectrum disorders. Annals of Neurology. 2015 May;77(5):866-76. Epub 2015 Mar 27 (Trainee publication, Doyle-Thomas KA). Senior Responsible Author.
  • Sussman D, Leung RC, Vogan VM, Lee W, Trelle S, Lin S, Cassel DB, Chakravarty MM, Lerch JP, Anagnostou E, Taylor MJ. The autism puzzle: Diffuse but not pervasive neuroanatomical abnormalities in children with ASD. NeuroImage: Clinical. 2015 Apr 15;15(8):170-179 (Trainee publication, Sussman D).Coauthor or Collaborator.
  • Mankad D, Dupuis A, Smile S, Roberts W, Brian J, Lui T, Genore L, Zaghloul D, Iaboni A, Marco PM, Anagnostou E. A randomized, placebo controlled trial of Omega-3 fatty acids in the treatment of young children with autism. Molecular Autism. 2015 Mar 21;6(18) (Trainee publication, Mankad D). Senior Responsible Author.
  • Ellegood J, Anagnostou E, Babineau BA, Crawley JN, Lin L, Genestine M, DiCicco-Bloom E, Lai JK, Foster JA, Peñagarikano O, Geschwind DH, Pacey LK, Hampson DR, Laliberté CL, Mills AA, Tam E, Osborne LR, Kouser M, Espinosa-Becerra F, Xuan Z, Powell CM, Raznahan A, Robins DM, Nakai N, Nakatani J, Takumi T, van Eede MC, Kerr TM, Muller C, Blakely RD, Veenstra-VanderWeele J, Henkelman RM, Lerch JP. 3D Visualization of the regional differences. Molecular Psychiatry, 2015 Feb; 20(1):1. Coauthor or Collaborator.
  • Kushki A, Khan A, Brian J, Anagnostou E. A Kalman filtering framework for physiological detection of anxiety-related arousal in children with autism spectrum disorder. IEEE Transactions on Biomedical Engineering. 2015 Mar;62(3):990-1000. Epub 2014 Dec 4 (Trainee publication, Kushki A). Senior Responsible Author.
  • Ellegood J, Anagnostou E, Babineau BA, Crawley JN, Lin L, Genestine M, DiCicco-Bloom E, Lai JK, Foster JA, Peñagarikano O, Geschwind DH, Pacey LK, Hampson DR, Laliberté CL, Mills AA, Tam E, Osborne LR, Kouser M, Espinosa-Becerra F, Xuan Z, Powell CM, Raznahan A, Robins DM, Nakai N, Nakatani J, Takumi T, van Eede MC, Kerr TM, Muller C, Blakely RD, Veenstra-VanderWeele J, Henkelman RM, Lerch JP. Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity. Mol Psychiatry. 2015 Feb;20(1):118-25. Coauthor or Collaborator.

2014

  • Vara AS, Pang EW, Vidal J, Anagnostou E, Taylor MJ. Neural mechanisms of inhibitory control continue to mature in adolescence. Dev Cogn Neurisci. 2014 Oct;10:129-139. Epub 2014 Aug 30 (Trainee publication, Vera AS). Coauthor or Collaborator.
  • Anagnostou E, Soorya L, Brian J, Dupuis A, Mankad D, Smile S, Jacob S. Intranasal oxytocin in the treatment of autism spectrum disorders: a review of literature and early safety and efficacy data in youth. Brain Research. 2014 Sep 11;1580:188-198. Epub 2014 Feb 5. Principal Author.
  • Kushki A, Brian J, Dupuis A, Anagnostou E. Functional autonomic nervous system profile in children with autism spectrum disorder. Molecular Autism. 2014 Jul;5:39 (Trainee publication, Kushki A). Senior Responsible Author.
  • Hadley D, We ZL, Kao C, Kini A, Mohamed-Hadley A, Thomas K, Vazquez L, Qiu H Mentch F, Pellegrino R, Kim C, Connolly J Anagnostou E, Glessner J, Hakonarson H; AGP Consortium. The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism. Nat Commun. 2014 Jun 13;5:4074. Coauthor or Collaborator.
  • Pinto D, Delaby E, Barbosa M, Merikangas A, Klei L, Thiruvahindrapuram B, Xu X, Ziman R, Wang Z, Vorstman JA, Anagnostou E, Thompson A, Regan R, Pilorge M, Pellecchia G, et al. Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. American Journal of Human Genetics. 2014 May 1;94(5):677-694. Epub 2014 April 24. Coauthor or Collaborator.
  • Anagnostou E, Zwaigenbaum L, Szatmari P, Fombonne E, Fernandez BA, Woodbury-Smith M, Brian J, Bryson S, Smith IM, Drmic I, Buchanan JA, Roberts W, Scherer SW. Autism spectrum disorder: advances in evidence-based practice. Canadian Medical Association Journal. 2014 Apr 15;186(7):509-519. Epub 2014 Jan 13. Principal Author.
  • Baribeau DAAnagnostou E. An update on medication management of behavioral disorders in autism. Current Psychiatry Rep. 2014 Mar;16(3):437 (Trainee publication, Baribeau DA). Senior Responsible Author.
  • Baribeau DA, Anagnostou E. Social Communication is an Emerging Target for Pharmacotherapy in Autism Spectrum Disorder - A Review of the Literature on Potential Agents. J Can Acad Child Adolesc Psychiatry. 2014 Feb;23(1):20-30 (Trainee publication, Baribeau DA). Senior Responsible Author.
  • Vara AS, Pang EW, Doyle-Thomas KA, Vidal J, Taylor MJ, Anagnostou E. Is inhibitory control a “no-go” in adolescents with autism spectrum disorder? Molecular Autism. 2014 Jan 31;5(1):6 (Trainee publication, Vara AS). Senior Responsible Author.
  • Eilam-Stock T, Xu P, Cao M, Gu X, Van Dam NT, Anagnostou E, Kolevzon A, Soorya L, Park Y, Siller M, He Y, Hof PR, Fan J. Abnormal autonomic and associated brain activities during rest in autism spectrum disorder. Brain. 2014 Jan;137(Pt 1):153-171. Coauthor or Collaborator.
  • Doyle-Thomas KA, Card D, Soorya LV, Wang AT, Fan J, Anagnostou E. Metabolic mapping of deep brain structures and associations with symptomatology in autism spectrum disorders. Res Autism Spectr Disord. 2014 Jan;8(1):44-51 (Trainee publication, Doyle-Thomas KA). Senior Responsible Author.

2013

  • Baribeau DAAnagnostou E. A comparison of neuroimaging findings in childhood onset schizophrenia and autism spectrum disorder: a review of the literature. Front Psychiatry. 2013 Dec 20;4:175 (Trainee publication, Baribeau DA). Senior Responsible Author.
  • King BH, Dukes K, Donnelly CL, Sikich L, McCracken JT, Scahill L, Hollander E, Bregman JD, Anagnostou E, Robinson F, Sullivan L, Hirtz D. Baseline factors predicting placebo response to treatment in children and adolescents with autism spectrum disorders: a multisite randomized clinical trial. JAMA Pediatrics. 2013 Nov;167(11):1045-1052. (indexed for MEDLINE). Coauthor or Collaborator.
  • Duerden EG, Taylor MJ, Soorya LV, Wang T, Fan J, Anagnostou E. Neural correlates of inhibition of socially relevant stimuli in adults with autism spectrum disorder. Brain Research. 2013 Oct 2;1533:80-90. Epub 2013 Aug 17. (Trainee publication, Duerden EG). Senior Responsible Author.
  • Ameis SH, Fan J, Rockel C, Soorya L, Wang AT, Anagnostou E. Altered cingulum bundle microstructure in autism spectrum disorder. Acta Neuropsychiatrica. 2013 Oct;25(5):275-282 (Trainee publication, Ameis SH). Senior Responsible Author.
  • Hallett V, Lecavalier L, Sukhodolsky DG, Cipriano N, Aman MG, McCracken JT, McDougle CJ, Tierney E, King BH, Hollander E, Sikich L, Bregman J,Anagnostou E, Donnelly C, Katsovich L, Dukes K, Vitiello B, Gadow K and Scahill L. Exploring the manifestations of anxiety in children with autism spectrum disorders. Journal of Autism and Developmental Disorders. 2013 Oct;43(10):2341-2352. Coauthor or Collaborator.
  • Mak-Fan KM, Morris D, Vidal J, Anagnostou E, Roberts W, Taylor MJ. White matter and development in children with an autism spectrum disorder. Autism. 2013 Sep;17(5):541-557. Epub 2012 Jun 14 (PubMed - indexed for MEDLINE) (Trainee publication, Mak-Fan KM). Coauthor or Collaborator.
  • Jiang YH, Yuen RK, Jin X, Wang M, Chen N, Wu X, Ju J, Mei J, Shi Y, He M, Wang G, Liang J, Wang Z, Cao D, Carter MT, Chrysler C, Drmic IE, Howe JL, Lau L, Marshall CR, Merico D, Nalpathamkalam T, Thiruvahindrapuram B, Thompson A, Uddin M, Walker S, Luo J, Anagnostou E, Zwaigenbaum L, Ring RH, Wang J, Lajonchere C, Wang J, Shih A, Szatmari P, Yang H, Dawson G, Li Y, Scherer SW. Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing. Am J Hum Genet. 2013 Aug 8;93(2):249-263. Epub 2013 Jul 11. Coauthor or Collaborator.
  • Fleury A, Kushki A, Tanel N, Anagnostou E, Chau T. Statistical persistence and timing characteristics of repetitive circle drawing in children with ASD. Developmental Neurorehabilitation. 2013 Aug;16(4):245-254 (Trainee publication, Fleury A). Co-Senior Responsible Author.
  • Doyle-Thomas KA, Kushki A, Duerden EG, Taylor MJ, Lerch JP, Soorya LV, Wang AT, Fan J, Anagnostou E. The effect of diagnosis, age, and symptom severity on cortical surface area in the cingulate cortex and insula in autism spectrum disorders. Journal of Child Neurology. 2013 Jun;28(6):732-739. Epub 2012 Jul 25 (indexed for MEDLINE) (Trainee publication, Kushki A, Doyle-Thomas KA). Senior Responsible Author.
  • Lionel AC, Vaags AK, Sato D, Gazzellone MJ, Mitchell EB, Chen HY, Costain G, Walker S, Egger G, Thiruvahindrapuram B, Merico D, Prasad A,Anagnostou E, Fombonne E, Zwaigenbaum L, Roberts W, Szatmari P, Fernandez BA, Georgieva L, Brzustowicz LM, Roetzer K, Kaschnitz W, Vincent JB, Windpassinger C, Marshall CR, Trifiletti RR, Kirmani S, Kirov G, Petek E, Hodge JC, Bassett AS and Scherer SW. Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures. Hum Mol Genet. 2013 May 15;22(10):2055-2066. Epub 2013 Feb 7.Coauthor or Collaborator.
  • Doyle-Thomas KA, Duerden EG, Taylor MJ, Lerch JP, Soorya LV, Wang AT, Fan J, Hollander E, Anagnostou E. Effects of age and symptomatology on cortical thickness in autism spectrum disorders. Res Autism Spectrum Disord. 2013 Jan;7(1):141-150 (Trainee publication, Doyle-Thomas, KA, Duerden EG).Senior Responsible Author.
  • Kushki A, Drumm E, Pla Mobarak M, Tanel N, Dupuis A, Chau T, Anagnostou E. Investigating the autonomic nervous system response to anxiety in children with autism spectrum disorders. PLoS One. 2013;8(4):e59730. Epub 2013 April 5 (Trainee publication, Kushki A). Senior Responsible Author.

2012

  • Anagnostou E, Soorya L, Chaplin W, Bartz J, Halpern D, Wasserman S, Wang AT, Pepa L, Tanel N, Kushki A, Hollander E. Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial. Mol Autism. 2012 Dec 5;3(1):16 (Trainee publication, Halpern D, Wang AT, Kushki A). Principal Author.
  • Smile S, Anagnostou E. New models for considering the role of medication in the treatment and elucidation of the etiology of autism. Current Psychiatry Reports. 2012 Dec;14(6):726-731. Co-Principal Author.
  • Anagnostou E. Translational Medicine: Mice and men show the way. Nature. 2012 Nov 8;491(7423):196-197. Principal Author.
  • Mahajan R, Bernal MP, Panzer R, Whitaker A, Roberts W, Handen B, Hardan A, Anagnostou E, Veenstra-VanderWeele J, Autism Speaks Autism Treatment Network Psychopharmacology Committee. Clinical practice pathways for evaluation and medication choice for attention-deficit/hyperactivity disorder symptoms in autism spectrum disorders. Pediatrics. 2012 Nov;130(Suppl 2):S125-138. Coauthor or Collaborator.
  • Coury DL, Anagnostou E, Manning-Courtney P, Reynolds A, Cole L, McCoy R, Whitaker A, Perrin JM. Use of psychotropic medication in children and adolescents with autism spectrum disorders. Pediatrics. 2012 Nov;130(Suppl 2):S69-76. Coauthor or Collaborator.
  • Fan J, Bernardi S, Van Dam NT, Anagnostou E, Gu X, Martin L, Park Y, Liu X, Kolevzon A, Soorya L, Grodberg D, Hollander E and Hof PR. Functional deficits of the attentional networks in autism. Brain Behav. 2012 Sep;2(5):647-660. Epub 2012 Aug 27. Coauthor or Collaborator.
  • Sato D, Lionel AC, Leblond CS, Prasad A, Pinto D, Walker S, O’Connor I, Russell C, Drmic IE, Hamdan FF, Michaud JL, Endris V, Roeth R, Delorme R, Huguet G, Leboyer M, Rastam M, Gillberg C, Lathrop M, Stavropoulos DJ, Anagnostou E, Weksberg R, Fombonne E, Zwaigenbaum L, Fernandez BA, Roberts W, Rappold GA, Marshall CR, Bourgeron T, Szatmari P and Scherer SW. SHANK1 Deletions in Males with Autism Spectrum Disorder. Am J Hum Genet. 2012 May 4;90(5):879-887. Epub 2012 Apr 12. Coauthor or Collaborator.
  • Scahill L, McCracken JT, Bearss K, Robinson F, Hollander E, King B, Bregman J, Sikich L, Dukes K, Sullivan L, Anagnostou E, Donnelly C, Kim YS, Ritz L, Hirtz D, Wagner A. Design and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders. J Autism Dev Disord. 2012 Mar;42(3):432-440. Coauthor or Collaborator.
  • Hollander E, Soorya L, Chaplin W, Anagnostou E, Taylor BP, Ferretti CJ, Wasserman S, Swanson E, Settipani C. A double-blind placebo-controlled trial of fluoxetine for repetitive behaviors and global severity in adult autism spectrum disorders. Am J Psychiatry. 2012 Mar;169(3):292-9. Erratum in: Am J Psychiatry. 2012 May;169(5):540. Coauthor or Collaborator.

2011

  • Girgis RR, Slifstein M, Xu X, Frankle WG, Anagnostou E, Wasserman S, Pepa L, Kolevzon A, Abi-Dargham A, Laruelle M, Hollander E. The 5-HT(2A) receptor and serotonin transporter in Asperger’s disorder: A PET study with [¹¹C]MDL 100907 and [¹¹C]DASB. Psychiatry Res. 2011 Dec 30;194(3):230-234. Epub 2011 Nov 12. Coauthor or Collaborator.
  • Anagnostou E, Hansen R. Medical treatment overview: traditional and novel psycho-pharmacological and complementary and alternative medications. Curr Opin Pediatr. 2011 Dec;23(6):621-627. Co-Principal Author.
  • Kushki A, Chau T, Anagnostou E. Handwriting difficulties in children with autism spectrum disorders: a scoping review. J Autism Dev Disord. 2011 Dec;41(12):1706-16. Erratum in: J Autism Dev Disord. 2011 Dec;41(12):1717. (Trainee publication, Kushki A). Senior Responsible Author.
  • Ameis SH, Fan J, Rockel C, Voineskos AN, Lobaugh NJ, Soorya L, Wang AT, Hollander E, Anagnostou E. Impaired structural connectivity of socio-emotional circuits in autism spectrum disorders: a diffusion tensor imaging study. PLoS One. 2011 Dec;6(11):e28044. Epub 2011 Nov 23. (Trainee publication, Ameis SH). Senior Responsible Author.
  • Anagnostou E, Chaplin W, Watner D, Silverman JM, Smith CJ, Zagursky K, Kryzak LA, Corwin TE, Feirsen N, Tanel N and Hollander E. Factor analysis of repetitive behaviors in Autism as measured by the Y-BOCS. J Neuropsychiatry Clin Neurosci. 2011 Jun;23(3):332-9. Principal Author.
  • Anagnostou E, Taylor MJ. Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here. Mol Autism. 2011 Apr 18;2(1):4. Principal Author.
  • Bernardi S, Anagnostou E, Shen J, Kolevzon A, Buxbaum JD, Hollander E, Hof PR, Fan J. In vivo 1H- magnetic resonance spectroscopy study of the attentional networks in autism. Brain Res. 2011 Mar 22;1380:198-205. Epub 2010 Dec 23. Coauthor or Collaborator.
  • Zwaigenbaum L, Scherer S, Szatmari P, Fombonne E, Bryson SE, Hyde K, Anagnostou E, Brian J, Evans A, Hall G, Nicholas D, Roberts W, Smith I, Vaillancourt T, Volden J. The NeuroDevNet Autism Spectrum Disorders Demonstration Project. Semin Pediatr Neurol. 2011 Mar;18(1):40-48. Erratum in: Semin Pediatr Neurol. 2013 Mar;20(1):57. Coauthor or Collaborator.

2010-2005

  • Georgiades S, Papageorgiou V, Anagnostou E. Brief report: Repetitive behaviours in Greek individuals with autism spectrum disorder. J Autism Dev Disord. 2010 Jul;40(7):903-6 (Trainee publication, Georgiades S). Senior Responsible Author.
  • Hollander E, Chaplin W, Soorya L, Wasserman S, Novotny S, Rusoff J, Feirsen N, Pepa L, Anagnostou E. Divalproex sodium vs placebo for the treatment of irritability in children and adolescents with autism spectrum disorders. Neuropsychopharmacology. 2010 Mar;35(4):990-8. Epub 2009 Dec 9. Senior Responsible Author.
  • King BH, Hollander E, Sikich L, McCracken JT, Scahill L, Bregman JD, Donnelly CL, Anagnostou E, Dukes K, Sullivan L, Hirtz D, Wagner A, Ritz L, STAART Psychopharmacology Network. Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism. Arch Gen Psychiatry. 2009 Jun;66(6):583-90. Coauthor or Collaborator.
  • Glessner JT, Wang K, Cai G, Korvatska O, Kim CE, Wood S, Zhang H, Estes A, Brune CW, Bradfield JP, Imielinski M, Frackelton EC, Reichert J, Crawford EL, Munson J, Sleiman PM, Chiavacci R, Annaiah K, Thomas K, Hou C, Glaberson W, Flory J, Otieno F, Garris M, Soorya L, Klei L, Piven J, Meyer KJ, Anagnostou E, Sakurai T, Game RM, Rudd DS, Zurawiecki D, McDougle CJ, Davis LK, Miller J, Posey DJ, Michaels S, Kolevzon A, Silverman JM, Bernier R, Levy SE, Schultz RT, Dawson G, Owley T, McMahon WM, Wassink TH, Sweeney JA, Nurnberger JI, Coon H, Sutcliffe JS, Minshew NJ, Grant SF, Bucan M, Cook EH, Buxbaum JD, Devlin B, Schellenberg GD and Hakonarson H. Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature. 2009 May 28;459(7246):569-73. Epub 2009 Apr 28. Coauthor or Collaborator.
  • Cai G, Edelmann L, Goldsmith JE, Cohen N, Nakamine A, Reichert JG, Hoffman EJ, Zurawiecki DM, Silverman JM, Hollander E, Soorya L, Anagnostou E, Betancur C and Buxbaum JD. Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: efficient identification of known microduplications and identification of a novel microduplication in ASMT. BMC Med Genomics. 2008 Oct 16;1:50. Coauthor or Collaborator.
  • Hollander E, Bartz J, Chaplin W, Phillips A, Sumner J, Soorya L, Anagnostou E and Wasserman S. Oxytocin increases retention of social cognition in autism. Biol Psychiatry. 2007 Feb 15;61(4):498-503. Epub 2006 Aug 14. Coauthor or Collaborator.
  • Wasserman S, Iyengar R, Chaplin WF, Watner D, Waldoks SE, Anagnostou E, Soorya L and Hollander E. Levetiracetam versus placebo in childhood and adolescent autism: a double-blind placebo-controlled study. Int Clin Psychopharmacol. 2006 Nov;21(6):363-7. Coauthor or Collaborator.
  • Anagnostou E, Esposito K, Soorya L, Chaplin W, Wasserman S and Hollander E. Divalproex versus placebo for the prevention of irritability associated with fluoxetine treatment in autism spectrum disorder. J Clin Psychopharmacol. 2006 Aug;26(4):444-6. Principal Author.
  • Hollander E, Soorya L, Wasserman S, Esposito K, Chaplin W, Anagnostou E. Divalproex sodium vs. placebo in the treatment of repetitive behaviours in autism spectrum disorder. Int J Neuropsychopharmacol. 2006 Apr;9(2):209-13. Epub 2005 Aug 15. Senior Responsible Author.
  • Anagnostou E, Hollander E. 4 drugs can improve autism’s repetitive behaviors: controlled trails shape evolving treatment approach. Current Psychiatry. 2006 Apr;5(4):55-64. Co-Principal Author.
  • Hollander E, Anagnostou E, Chaplin W, Esposito K, Haznedar MM, Licalzi E, Wasserman S, Soorya L, Buchsbaum M. Striatal volume on magnetic resonance imaging and repetitive behaviors in autism. Biol Psychiatry. 2005 Aug 1;58(3):226-32. Co-Principal Author.
  • Anagnostou E, Miller SP, Guiot MC, Karpati G, Simard L, Dilenge ME and Shevell MI. Type I spinal muscular atrophy can mimic sensory-motor axonal neuropathy. J Child Neurol. 2005 Feb;20(2):147-50. Principal Author.

Books

Anagnostou E, Brian J, editor(s). Clinician’s Manual: Autism Spectrum Disorder. (Switzerland): Springer International Publishing Switzerland; 2015. ISBN: 978-3-919-03055-5 ISBN: 978-2-319-03056-2 (eBook). Co-Editors.

Hollander E, Anagnostou E (Co-Editors)., editor(s). Clinical Manual for the Treatment of Autism. (Japan): Tuttle - Mori Agency Inc; 2013. Japanese translation rights arranged with APPI c/o John Scott & Company through Tuttle-Mori Agency Inc. Tokyo. Co-Editor.

Clinical Manual for the Treatment of Autism. American Psychiatric Publishing, Inc. 2013  ISBN 1585622222, 9781585622221. Co-Editor

Book Chapters

Baribeau DA, Anagnostou E. Neuroimaging in Autism Spectrum Disorders. In: S.H. Fatemi (Ed.), editor(s). Molecular Autism. Springer Publishing Company; 2015

Anagnostou E, Mankad D. Future Direction in Psychopharmacology of Autism Spectrum Disorder. In: Valerie W. Hu, editor(s). Frontiers in Autism Research New Horizons for Diagnosis and Treatment. World Scientific Publishing Co.; 2014. p. 473-495.

Wang M, Anagnostou E. Using virtual reality as a treatment tool for children with autism. In: Patel, VinoodB.; Victor R.; Martin, Colin R., editor(s). Comprehensive Guide to Autism. Spinger Inc; 2014. p. 2125-2126

Anagnostou E, McKeever C, Kushki A. Novel therapeutics in autism spectrum disorders. In: Buxbaum J, Hof P, editor(s). The Neuroscience of autism spectrum disorders. Elsevier; 2012. p. 85-193. ISBN: 978-0-12-391924-3

Anagnostou E, Bear M, Dawson G. Commentary: Future directions in the treatment of autism spectrum disorders. In: Amaral D, Dawson G, Gerschwind D, editor(s). Autism Spectrum Disorders. New York (United States): Oxford University Press; 2011. p. 1259-1268.

Anagnostou E, Rusoff J. Anticonvulstants in the treatment of autism. In: Hollander E, Kolevzon A, Coyle J, editor(s). Autism Textbook of Autism Spectrum Disorders. APPI Press; 2011. p. 457-467.

Anagnostou E, Shevell M. Outcomes in Autism. Autism: A Neurological Disorder of Early Brain Development. MacKeith Press; 2006

Anagnostou E, Hollander E. Autism Spectrum Disorders. In: Neurological and Psychiatric Disorders. Humana Press; 2005. p. 131-149.


Contact Info

Contact Information:

Bloorview Research Institute
Holland Bloorview Kids Rehabilitation Hospital 
150 Kilgour Road Toronto, ON M4G 1R8 
T: 416-425-6220 x. 6005  F: 416-422-7045

Contact Email:
eanagnostou@hollandbloorview.ca